IG Workshop 2007
Genetics Mysteries
February 21 Meet with Dr.s' Peterson, Voytas, Dobbs and Kanthasamy to discuss expectations of the course. Students may sign up for a minimum of two chalk talks at that time.
February 28 Thomas Peterson thomasp@iastate.edu will present Jiming Jiang, Horticulture, University of Wisconsin-Madison
March 7 Drena Dobbs ddobbs@iastate.edu will present Susan Lolle, Dept of Biology, University of Waterloo in Ontario, Canada
March 21 Anumantha Kanthasamy akanthas@iastate.edu will present Stanley Prusiner, Neuroscience, University of California, San Francisco
March 28 Dan Voytas voytas@iastate.edu will present Amar Klar, Head, Developmental GeneticsGene Regulation and Chromosome Biology National Cancer Institute, Frederick MD
Students must attend all discussion sessions and read all papers that pertain to that speaker prior to coming to class. The class will be divided into small groups for discussion and will present the results of the discussion to the rest of the class.
[Students who fail to attend discussion sessions must read all papers and write an acceptable one-page (single spaced, 12 point, .7 inch margins) discussion of the major points for each paper. These papers should be submitted to the faculty member who presented the speaker.]
Students must attend all public presentations and two chalk talks. Students who fail to attend a public presentation may check out a DVD of the talk and write an acceptable one-page paper on the seminar. This paper should be submitted to the faculty member who is hosting the speaker.
Chalk Talks:
Students enrolled in GENET 591 only
Students need to attend two chalk talks
Students will sign up for both chalk talks at the Feb 21 meeting.
Monday, April 2 368 Heady Hall 11:30 Prusiner
Wednesday April 11 1102 Molecular Biology noon Lolle
Wednesday April 18 1102 Molecular Biology noon Jiang
Tuesday, April 24 368 Heady Hall 9:00 a.m. Klar
Speaker: Dr. Stanley Prusiner, MD
Affliation: Neuroscience, University of California, San Franciso
Title of Seminar: "Prion Biology and Diseases"
Date: Monday, April 2, 2007
Location: 1210 LeBaron Hall
Time: 4:15 p.m.
Website of Speaker
Research: Infectious proteins called prions that cause neurodegenerative diseases
ISU Contact: Anumantha Kanthasamy, Biomedical Sciences
CHALK TALK: 11:30 in 368 Heady Hall
Only students enrolled in GENET 591 can attend. We can not eat in this room so we may have food outside
at 11:30 a.m. for lunch, but you have to eat there too. Only drinks can be taken into the Ensminger Room.
PUBLICATIONS: READ FOR CLASS
Huang et al., PNAS
Legname et al., PNAS
Manuelidis, et. al Cells infected with
scrapie and Creutzfeldt-Jakob disease agents produce intracellular 25-nm virus-like particles.
Prusiner. Prions. Adapted by The Nobel
Foundation PNAS.
Instructions for Class Discussion
Speaker: Susan Lolle, Professor
Affliation: Department of Biology, University of Waterloo in Ontario, Canada
Title of Seminar: TBA
Date: Tuesday, April 10, 2007
Location: 1414 Molecular Biology
Time: 4:10 p.m.
Refreshments: 3:45 p.m. in the Atrium of the Molecular Biology Building
Website of Speaker
Research: "Genome-wide non-Mendelian inheritance of extra-genomic information in Arabidopsis."
See Bob Pruitt, Purdue
ISU Contact: Drena Dobbs, Genetics, Development and Cell Biology
CHALK TALK: Noon, Wednesday, April 11, 1102 Molecular Biology
Location may be moved due to large number of students who wish to attend
.
PUBLICATIONS: READ FOR CLASS
Nature Molinier 442
Nature Rassoulzadegan 441
New Phytologist Chen
Nature Peng et al
Roth et al 121
Lolle Asssignment
Krishnaswamy paper
Lolle Nature 2005 paper
Speaker: Jiming Jiang, Professor
Affliation: Horticulture, University of Wisconsin-Madison
Title of Seminar: "Centromere: supposed to be silent, makes lots of noise"
Date: Tuesday, April 17, 2007
Location: 1414 Molecular Biology
Time: 4:10 p.m.
Refreshments: 3:45 p.m. in the Atrium of the Molecular Biology Building
Website of Speaker
Research: "Although the functions of centromeres are conserved in all eukaryotes,
the primary DNA sequence that underlies centromeres has no discernable conservation among model
eukaryotes, which has been one of the most intriguing enigmas in biology."
ISU Contact: Tom Peterson, Genetics, Development and Cell Biology
CHALK TALK: Noon, Wednesday, April 18, 1102 Molecular Biology
PUBLICATIONS: Read for class
1. Jiang, J., Nasuda, S., Dong, F., Scherrer, C.W.,
Woo, S.-S., Wing, R.A., Gill, B.S., and Ward, D.C. (1996) A conserved repetitive DNA element located in the
centromeres of cereal chromosomes. Proc. Natl. Acad. Sci. USA 93: 14210-14213.
2.Henikoff, S., Ahmad, K., and Malik, H.S. (2001). The centromere paradox: stable inheritance with
rapidly evolving DNA. Science 293, 1098-1102.
3. Nagaki, K., Cheng, Z.K., Ouyang, S., Talbert, P.B., Kim, M., Jones, K.M., Henikoff, S., Buell, C.R.,
and Jiang, J. (2004) Sequencing of a rice centromere uncovers active genes. Nature Genet. 36: 138-145.
Speaker: Amar Klar, Head, Developmental Genetics Section
Affliation: Gene Regulation and Chromosome Biology Laboratory, National Cancer Institute, Frederick, MD
Title of Seminar: "Asymmetric cell division through selective chromatid segregation as a mechanism for human left
versus right hand-use preference, brain laterality, psychosis traits and vertebrates visceral laterality
development"
Date: Monday, April 23, 2007
Location: 1414 Molecular Biology
Time: 4:10 p.m.
Refreshments: 3:45 p.m. in the Atrium of the Molecular Biology Building
Website of Speaker
Research: "The genetics of left-handedness and schizophrenia."
ISU Contact: Dan Voytas, Genetics, Development and Cell Biology
CHALK TALK: 9:00 Tuesday, April 24, in 368 Heady Hall
PUBLICATIONS: READ FOR CLASS
Psychosis 2004
Armakolas & Klar 2006
Armakolas & Klar Sapienza Science 2007